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1.
Ⅱ期临床试验的主要目的是对药物治疗的安全性和有效性进行评估.针对具有高安全性的Ⅱ期两阶段临床试验,给出小样本量下关于安全性和有效性的精确检验方法,并证明最大Ⅰ类错误概率与Ⅱ类错误概率分别在原假设和备择假设的边界处达到.在期望样本量最小原则下,给出最优两阶段设计的构造方法和常用设计表,供实际应用选用.  相似文献   
2.
The essence of mutual insurance is the notion that re-distributing risk in a pool of risks is more beneficial than taking the risk alone. Interpreting ‘more beneficial’ as an increase in utility and considering sequences of exchangeable risks, we are able to formalize this notion from the policyholder’s perspective and demonstrate its validity for various alternative preference functionals (e.g., expected utility, Choquet expected utility, and distortion risk measures). To obtain this result, we exploit that for a sequence of exchangeable risks the corresponding sequence of arithmetical averages is a reversed martingale.We conclude that pooling risks is fundamental for understanding the mechanisms of insurance because it favourably affects the utility of policyholders, and we refer to this phenomenon as the ‘utility-improving effect of risk pooling’. Moreover, we demonstrate that the utility of the policyholder is (strictly) increasing with the size of the risk pool.  相似文献   
3.
This paper extends the framework for the valuation of life insurance policies and annuities by Andrés-Sánchez and González-Vila (2012, 2014) in two ways. First we allow various uncertain magnitudes to be estimated by means of fuzzy numbers. This applies not only to interest rates but also to the amounts to be paid out by the insurance company. Second, the use of symmetrical triangular fuzzy numbers allows us to obtain expressions for the pricing of life contingencies and their variability that are closely linked to standard financial and actuarial mathematics. Moreover, they are relatively straightforward to compute and understand from a standard actuarial point of view.  相似文献   
4.
Yang and Qiu proposed and reframed an expected utility–entropy (EU-E) based decision model. Later on, a similar numerical representation for a risky choice was axiomatically developed by Luce et al. under the condition of segregation. Recently, we established a fund rating approach based on the EU-E decision model and Morningstar ratings. In this paper, we apply the approach to US mutual funds and construct portfolios using the best rating funds. Furthermore, we evaluate the performance of the fund ratings based on the EU-E decision model against Morningstar ratings by examining the performance of the three models in portfolio selection. The conclusions show that portfolios constructed using the ratings based on the EU-E models with moderate tradeoff coefficients perform better than those constructed using Morningstar. The conclusion is robust to different rebalancing intervals.  相似文献   
5.
In a stochastic convex feasibility problem connected with a complete probability space (Ω,A,μ) and a family of closed convex sets (Cω)ωεΩ in a real Hilbert space H, one wants to find a point that belongs to Cω for μ almost all ω ε Ω. We present a projection based method where the variable relaxation parameter is defined by a geometrical condition, leading to an iteration sequence that is always weakly convergent to a μ almost common point. We then give a general condition assuring norm convergence of this equation to that μ almost common point  相似文献   
6.
介绍一种计算随机变量数学期望的方法,利用这种方法容易得到数学期望的相关性质,很多概率与矩的不等式证明也因之变得更为简洁.  相似文献   
7.
《Optimization》2012,61(5):743-754
In this paper the problem of estimation of an optimal replacement interval for a system which is minimally repaired at failures is studied. The problem is investigated both under a parametric and a nonparametric form of the failure intensity of the system. It is assumed that observational data from n systems are available. Some asymptotic results are shown. A graphical procedure for determining/estimating an optimal replacement interval is presented. The procedure is particularly valuable for sensitivity analyses, for example with respect to the costs involved.  相似文献   
8.
本文重点讨论了在离散时刻对投资组合进行调整的CPPI策略.给出了组合价值的过程表达式,并对其进行风险分析;引入二次期望效用函数,给出了确定CPPI策略中最优乘数的方法;讨论了借贷限制对CPPI策略的影响并将其与买入持有策略进行比较分析。最后,文章对CPPI策略的投资效果进行了实证分析.  相似文献   
9.
Fuzzy number approximation by trapezoidal fuzzy numbers which preserves the expected interval is discussed. Algorithms for calculating the proper approximations are proposed and some properties of the approximation operators are discussed. It is shown that an adequate approximation operator might be chosen through the comparisons of some characteristics of the fuzzy number, like its ambiguity, width, its value and weighted expected value.  相似文献   
10.
本文探讨具有违约风险的人寿保险的最优定价.我们从Black-Scholes的期权定价模型出发,考虑风险管理和准备金的要求,根据一次支付和均衡支付这两种不同的假设分别建立两个优化模型,并且借助于优化技术获得最优解.数量化分析结果表明,两个模型的最优价格对于利息率参数以及非索赔成本的变化都不敏感.这说明这两个模型是稳定的,而且是实用的.  相似文献   
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